6533b7d9fe1ef96bd126c40f

RESEARCH PRODUCT

Phenolic glycosides from Phagnalon rupestre.

M. Carmen RecioJosé Luis RíosLuis GóngoraAlexander I. GrayRosa M. GinerSalvador Máñez

subject

StereochemistryPiceinFlavonoidMolecular ConformationPlant ScienceHorticultureAsteraceaeBiochemistryLignanschemistry.chemical_compoundOrganic chemistryPhenolsGlycosidesMolecular BiologyLignanchemistry.chemical_classificationbiologyQuinonesGlycosideAcetophenonesGeneral MedicineAsteraceaebiology.organism_classificationchemistryApigeninPlant ShootsAcetophenone

description

Analysis of the butanol-soluble fraction from the methanolic extract of the aerial parts of Phagnalon rupestre (Asteraceae) has led to the isolation of seven phenolic compounds. Three have been identified on the basis of their NMR spectra as new natural compounds: the lignan 7,7'-bis-(4-hydroxy-3,5-dimethoxyphenyl)-8,8'-dihydroxymethyl-tetrahydrofuran-4-O-beta-glucopyranoside (1), the prenylhydroquinone glycoside 1-O-beta-glucopyranosyl-1,4-dihydroxy-2-(3'-hydroxy-3'-methylbutyl) benzene (2) and the acetophenone glycoside 12-O-beta-glucopyranosyl-9beta,12-dihydroxytremetone (3). The known flavonoids apigenin-7-O-beta-glucoside, luteolin-7-O-beta-glucoside, luteolin-7-O-beta-glucuronide and the acetophenone picein were also isolated.

10.1016/s0031-9422(02)00011-0https://pubmed.ncbi.nlm.nih.gov/11937166