6533b7d9fe1ef96bd126c88e

RESEARCH PRODUCT

Antimicrobial consumption and antimicrobial resistance: A snapshot of an Italian neuromuscular rehabilitation center

G. BarberiMc ColaP. UtriS. MelardiB. AlagnaP. BramantiAntonio Cascio

subject

Microbiology (medical)GastrointestinalCathetersBacteriaSettore MED/17 - Malattie InfettiveAntimicrobial consumption; Antimicrobial resistance; DDD per 1000 patient-days; Healthcare-associated infections; Rehabilitation hospital; Anti-Bacterial Agents; Bacteria; Catheters; Drug Utilization; Intubation Gastrointestinal; Italy; Neuromuscular Diseases; Risk Factors; Drug Resistance Bacterial; Rehabilitation CentersHealthcare-Associated infections.Drug ResistanceBacterialNeuromuscular DiseasesHealthcare-associated infectionsAntimicrobial resistanceRehabilitation hospitalDDD per 1000 patient-daysRehabilitation CentersDrug UtilizationAnti-Bacterial AgentsItalyRisk FactorsAntimicrobial consumptionDrug Resistance BacterialIntubationIntubation GastrointestinalAntimicrobial consumption; Antimicrobial resistance; DDD per 1000 patient-days; Healthcare-Associated infections.; Rehabilitation hospital; Microbiology (medical)DDD per 1000 patient-day

description

The paper presents a snapshot of the incidence of antimicrobial-resistant microorganisms and antimicrobial consumption in an Italian rehabilitation center over a two-year period (2014-2015). Data on microorganism identification and antimicrobial susceptibility testing were obtained from the diagnostic laboratory of the hospital. A set of indicators was assessed, including the incidence density of resistant isolates per 1000 patient-days (IDRI). Data on antimicrobial consumption, semi-annually, obtained from the hospital pharmacy, were expressed as Defined Daily Dose (DDD) per 1000 patient-days. The most frequently isolated microorganism was Klebsiella pneumoniae (19.3%), and a significant increase in piperacillin/tazobactam- resistant K. pneumoniae (p=0.04) was observed. Among all antimicrobials used, carbapenems were the most prescribed antibiotic class (31%).

yearjournalcountryeditionlanguage
2017-05-15
https://iris.unipa.it/handle/10447/290589