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RESEARCH PRODUCT
ChemInform Abstract: Highly Enantioselective Aza-Henry Reaction with Isatin N-Boc Ketimines.
Melireth HolmquistJosé R. PedroGonzalo Blaysubject
chemistry.chemical_compoundNitroaldol reactionchemistryNitromethaneIsatinEnantioselective synthesisGeneral MedicineMedicinal chemistrydescription
The asymmetric aza-Henry reaction of isatin N-Boc-ketimines (I) with nitromethane in the presence of a Cu-Ph-box complex leads to a series of N-Boc-protected nitroamines (III) with high enantioselectivity in most cases.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2014-12-22 | ChemInform |