Large differences in metabolic activation and inactivation of chemically closely related compounds: effects of pure enzymes and enzyme induction on the mutagenicity of the twelve monomethylated benz[a]anthracenes, 7,12-dimethylbenz[a]anthracene and benz[a]anthracenes in the Ames test

6533b7d9fe1ef96bd126cd5d

RESEARCH PRODUCT

Large differences in metabolic activation and inactivation of chemically closely related compounds: effects of pure enzymes and enzyme induction on the mutagenicity of the twelve monomethylated benz[a]anthracenes, 7,12-dimethylbenz[a]anthracene and benz[a]anthracenes in the Ames test

Peter J. Sims Franz Oesch Hansruedi Glatt Klaus Vogel Philip Bentley

subject

Male Aroclors Cancer Research Ames test Mice chemistry.chemical_compound Benz(a)Anthracenes medicine Animals Benz(a)Anthracenes Enzyme inducer Biotransformation Epoxide Hydrolases chemistry.chemical_classification Mice Inbred C3H biology Mutagenicity Tests Chemistry 7 12-Dimethylbenz[a]anthracene General Medicine Chlorodiphenyl (54% Chlorine)Enzymes Cytosol Enzyme Biochemistry Enzyme Induction Phenobarbital biology.protein Phenobarbital Dihydrodiol dehydrogenase Methylcholanthrene Mutagens medicine.drug

year	journal	country	edition	language
1981-01-01	Carcinogenesis

https://doi.org/10.1093/carcin/2.9.813

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