6533b7d9fe1ef96bd126d4e5

RESEARCH PRODUCT

Syntheses of Some Biologically Active Compounds from Stilbenes Isolated from the Bark ofPicea abies

Antti TalvitieErkki KolehmainenErkki Mannila

subject

biologyChemistryOrganic ChemistryHuman immunodeficiency virus (HIV)Picea abiesBiological activitymedicine.disease_causebiology.organism_classificationchemistry.chemical_compoundvisual_artmedicinevisual_art.visual_art_mediumOrganic chemistryBarkPhenolsPhysical and Theoretical Chemistry

description

From the four stilbenes 1–4 isolated from the bark of Picea abies seven compounds 5–11 were obtained by hydrogenation or permethylation. 1H-, 13C-NMR and mass spectra were used for their characterization. The antileukemic activity of each compound was preliminary tested. Some compounds were further tested for their anti-HIV activity.

https://doi.org/10.1002/jlac.199219920170