6533b7d9fe1ef96bd126d52f

RESEARCH PRODUCT

Gekreuzt konjugierte oligomere aus pyrrol-, benzol- und carbonyl-Bausteinen

Herbert MeierSabine HinneschiedtA. Hormaza

subject

chemistry.chemical_compoundchemistryStereochemistryOrganic ChemistryDrug DiscoveryCross-conjugationSolubilityBenzeneBiochemistryEnone

description

Abstract Chalcones can serve as C 2 or C 3 components for the formation of 1 H -pyrroles. In particular the reaction with tosylisocyanid could be applied to the oligochalcones 2d - g with up to 6 enone units. A series of cross-conjugated oligomers 8d - g was obtained; these compounds consist of a chain of 1,4-phenylene, carbonyl and 1 H -pyrrole-3,4-diyl building blocks. The benzene rings bear two propoxy sidechains in order to enhance the solubility.

https://doi.org/10.1016/j.tet.2003.08.072