6533b7dafe1ef96bd126d942
RESEARCH PRODUCT
ILCs and T Cells Competing for Space: More Than a Numbers Game.
Georg GasteigerGeorg GasteigerGeorg GasteigerChristin FriedrichChristin Friedrichsubject
0301 basic medicinemedicine.medical_treatmentInterleukin-7T-LymphocytesImmunologyInnate immunologyInnate lymphoid cellBiologyT-cell homeostasisImmunity Innate03 medical and health sciences030104 developmental biology0302 clinical medicineInfectious DiseasesCytokineLymphatic systemImmunityImmunologymedicineImmunology and AllergyCytokinesHumansLymphocytesHomeostasis030215 immunologydescription
T cell homeostasis critically depends on interleukin-7 (IL-7). In this issue of Immunity, Martin et al. (2017) provide evidence that IL-7 availability is regulated through a "cytokine sink" involving innate lymphoid cells that compete for and consume IL-7 and thereby restrict T cell homeostasis in lymphoid organs.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2017-07-21 | Immunity |