6533b7dafe1ef96bd126de9f
RESEARCH PRODUCT
Propriétés et performances de phosphines ferrocéniques dans le couplage C-O, C-S et C-N : nouvelles méthodologies de synthèse au palladium
Mélanie Platonsubject
Aryl-heteroaryl sulfidesThioéthers d'aryle et d'hétéroaryleLiaison carbone-hétéroatomeÉthers d'aryle et d'hétéroarylePolyphosphines ferrocéniquesCarbon-heteroatom bondHomogeneous catalysisFerrocenyl polyphosphanesAryl-heteroaryl ethersDiarylaminesBiarylaminesCatalyse homogène[CHIM.OTHE] Chemical Sciences/Other[ CHIM.OTHE ] Chemical Sciences/Other[CHIM.OTHE]Chemical Sciences/OtherTriarylaminesPalladiumdescription
Multidentate ligands usually show great activities in low loading organometallic catalysis in palladium. Among these ligands, the use of ferrocenyl polyphosphane ligands give interesting results. Robust palladium-ferrocenyl triphosphane catalytic systems have permitted to obtain biarylamines and aryl-heteroaryl ethers in the presence of low catalytic loadings. DFT studies on catalytic cycle during formation of aryl-heteroaryl ethers were carried out. The presence of third phosphino group stabilizes a transition state which enhances the rate of the reductive elimination. Triarylamines were obtained with ferrocenyl diphosphane in the presence of 2 mol% of palladium loading. Moderate to excellent results were obtained. Finally, aryl-heteroaryl sulfides were obtained with excellent results with ferrocenyl tetraphosphane ligand in the presence of 0.2 mol% of palladium.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2012-07-23 |