6533b7dafe1ef96bd126eb35
RESEARCH PRODUCT
Enantioselective Addition of Dimethylzinc to Aldehydes Catalyzed by N-Substituted Mandelamide-Ti(IV) Complexes.
Gonzalo BlayVictor Hernandez‐olmosAlicia Marco‐aleixandreIsabel FernándezJosé R. Pedrosubject
Addition reactionChemistryOrganic ChemistryDimethylzincEnantioselective synthesisGeneral MedicineMedicinal chemistryCatalysisCatalysisInorganic Chemistrychemistry.chemical_compoundOrganic chemistryPhysical and Theoretical ChemistryTitanium isopropoxideMandelamidedescription
Abstract Amides derived from ( S )-(+)-mandelic acid in the presence of titanium isopropoxide catalyze the enantioselective addition of dimethylzinc to aromatic aldehydes with good yields and ee up to 90%.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2005-10-25 | ChemInform |