6533b7dafe1ef96bd126ec1c

RESEARCH PRODUCT

Automated detection and localization system of myocardial infarction in single-beat ECG using Dual-Q TQWT and wavelet packet tensor decomposition.

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Abstract Background and objective It is challenging to conduct real-time identification of myocardial infarction (MI) due to artifact corruption and high dimensionality of multi-lead electrocardiogram (ECG). In the present study, we proposed an automated single-beat MI detection and localization system using dual-Q tunable Q-factor wavelet transformation (Dual-Q TQWT) denoising algorithm. Methods After denoising and segmentation of ECG, a fourth-order wavelet tensor (leads × subbands × samples × beats) was constructed based on the discrete wavelet packet transform (DWPT), to represent the features considering the information of inter-beat, intra-beat, inter-frequency, and inter-lead. To reduce the tensor dimension and preserve the intrinsic information, the multilinear principal component analysis (MPCA) was employed. Afterward, 84 discriminate features were fed into a classifier of bootstrap-aggregated decision trees (Treebagger). A total of 78 healthy and 328 MI (6 types) records including 57557 beats were chosen from PTB diagnostic ECG database for evaluation. Results The validation results demonstrated that our proposed MI detection and localization system embedded with Dual-Q TQWT and wavelet packet tensor decomposition outperformed commonly used discrete wavelet transform (DWT), empirical mode decomposition (EMD) denoising methods and vector-based PCA method. With the Treebagger classifier, we obtained an accuracy of 99.98% in beat level and an accuracy of 97.46% in record level training/testing for MI detection. We also achieved an accuracy of 99.87% in beat level and an accuracy of 90.39% in record level for MI localization. Conclusion Altogether, the automated system brings potential improvement in automated detection and localization of MI in clinical practice.