RESUMEN EJECUTIVO DEL CONSENSO DE EXPERTOS SOBRE LA EFICACIA Y SEGURIDAD DE LOS iDPP-4 EN EL TRATAMIENTO DE PACIENTES CON DIABETES Y COVID-19

6533b7dbfe1ef96bd126f7d7

RESEARCH PRODUCT

RESUMEN EJECUTIVO DEL CONSENSO DE EXPERTOS SOBRE LA EFICACIA Y SEGURIDAD DE LOS iDPP-4 EN EL TRATAMIENTO DE PACIENTES CON DIABETES Y COVID-19

Domingo Orozco-beltrán Manuel Antonio Ruiz Quintero Pedro José Pinés Corrales Ricardo Gómez-huelgas Enrique Carretero-anibarro Juan Francisco Merino-torres Francisco Javier Carrasco-sánchez Manuel Gargallo

subject

Nutrition and Dietetics diabetes Endocrinology Diabetes and Metabolism Antidiabetic drugs Diabetes COVID-19 antidiabetic drugs iDPP-4 mortality Article Endocrinology mortalidad Mortality fármacos antidiabéticos

description

Resumen Antecedentes El objetivo de este consenso es esclarecer el papel de los iDPP-4 en el manejo de los pacientes con diabetes durante la pandemia por COVID-19. Material y metodos Se llevo a cabo una busqueda bibliografica en PubMed (diciembre 2019-febrero de 2021). Se empleo la metodologia Oxford y se establecieron de forma consensuada posibles recomendaciones. Resultados La diabetes parece ser un factor independiente en la enfermedad de COVID-19 (evidencia 2b). No se demuestra mayor riesgo de contagio con iDPP-4 (evidencia 2b), y su uso ha demostrado ser seguro (evidencia 2b). Los iDPP-4 pueden presentar un cierto beneficio en la reduccion de la mortalidad, particularmente su uso intrahospitalario (evidencia 2a), reduciendo la admision a unidades de cuidados intensivos (evidencia 2b) y la necesidad de ventilacion mecanica (evidencia 2b). Conclusiones Los iDPP-4 parecen ser farmacos seguros en pacientes con COVID-19, y se necesitan estudios de calidad que aclaren sus posibles ventajas.

year	journal	country	edition	language
2021-11-01	Endocrinologia, Diabetes Y Nutricion

10.1016/j.endinu.2021.10.003 http://europepmc.org/articles/PMC8570981

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