6533b7dbfe1ef96bd126f877
RESEARCH PRODUCT
Stereoselective synthesis of 2-amino-1-hydroxy-3-phenylpropylphosphonic acid
Jan ZygmuntPaweł KafarskiRoman GancarzPiotr WieczorekBarbara Lejczaksubject
Chemistryorganic chemicalsOrganic ChemistryClinical BiochemistryDrug DiscoveryPharmaceutical ScienceMolecular MedicineOrganic chemistryheterocyclic compoundsStereoselectivityEnantiomerMolecular BiologyBiochemistrydescription
Abstract A highly stereoselective synthesis of 2-amino-1-hydroxy-3-phenylpropylphosphonic acid was achieved by simple addition of diethyl phosphite to enantiomeric N-blocked phenylalaninals. These compouds exhibit significant herbicidal activity.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1996-12-01 | Bioorganic & Medicinal Chemistry Letters : a tetrahedron publication for the rapid dissemination of preliminary communication and all aspects of bioorganic chemistry, medicinal chemistry and related disciplines |