6533b7dbfe1ef96bd126fea8

RESEARCH PRODUCT

5 The Ascomycetous Cell Wall: From a Proteomic Perspective

Albert D. De BoerEulogio ValentínPiet W. J. De GrootBernd W. Brandt

subject

0301 basic medicineFirst contactchemistry.chemical_classification030106 microbiologyBiologyProteomicsGenomeCell biologyCell wall03 medical and health sciences030104 developmental biologychemistryOrganelleCell shapeGlycoprotein

description

Cell walls are essential organelles for fungi; they define cell shape during growth and provide osmotic integrity and protection against harmful influences in the growth environment. Fungal walls also play an important role in developing fungal infections as they form the first contact between the pathogen and the host immune system. In many ascomycetes, the cell wall consists of a polysaccharide matrix surrounded by a layer of covalently bound glycoproteins. With the complete genome sequences being available for many species, cell wall research in recent years has largely focused on identifying and elucidating the functions of cell wall proteins. In this chapter, we discuss, with a main focus on proteomics, new insights and advances in fungal cell wall research.

yearjournalcountryeditionlanguage
2016-01-01
https://doi.org/10.1007/978-3-319-25844-7_5