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RESEARCH PRODUCT

Use of Machine Learning and Artificial Intelligence to Drive Personalized Medicine Approaches for Spine Care

Michael G. FehlingsMichael G. FehlingsOmar F. KhanJetan H. BadhiwalaJetan H. BadhiwalaGiovanni Grasso

subject

Traumatic spinal cord injuryPrognosiPsychological interventionPatient characteristicsDiseaseSpinal cord injuryMachine learningcomputer.software_genreSpinal DiseaseMachine Learning03 medical and health sciences0302 clinical medicineArtificial IntelligenceHealth careFunctional StatuMedicineHumansSpine carePrecision MedicineDegenerative cervical myelopathyPrognostic modelsSpinal Cord InjuriesNatural Language ProcessingSpinal Cord Injuriebusiness.industryPrognosisPersonalized medicineFunctional Status030220 oncology & carcinogenesisSurgeryFunctional statusSpinal DiseasesNeurology (clinical)Personalized medicineArtificial intelligenceSpondylosisbusinesscomputerSpinal Cord Compression030217 neurology & neurosurgeryHuman

description

Personalized medicine is a new paradigm of healthcare in which interventions are based on individual patient characteristics rather than on “one-size-fits-all” guidelines. As epidemiological datasets continue to burgeon in size and complexity, powerful methods such as statistical machine learning and artificial intelligence (AI) become necessary to interpret and develop prognostic models from underlying data. Through such analysis, machine learning can be used to facilitate personalized medicine via its precise predictions. Additionally, other AI tools, such as natural language processing and computer vision, can play an instrumental part in personalizing the care provided to patients with spine disease. In the present report, we discuss the current strides made in incorporating AI into research on spine disease, especially traumatic spinal cord injury and degenerative spine disease. We describe studies using AI to build accurate prognostic models, extract important information from medical reports via natural language processing, and evaluate functional status in a granular manner using computer vision. Through a case illustration, we have demonstrated how these breakthroughs can facilitate an increased role for more personalized medicine and, thus, change the landscape of spine care.

10.1016/j.wneu.2020.04.022http://hdl.handle.net/10447/487581