6533b7dbfe1ef96bd12701e5
RESEARCH PRODUCT
Evaluation of a novel chromogenic medium for Candida spp. identification and comparison with CHROMagar™ Candida for the detection of Candida auris in surveillance samples.
Concepción Gimeno CardonaCarme Salvador GarcíaJuan V Mulet BayonaNuria Tormo Palopsubject
0301 basic medicineMicrobiology (medical)030106 microbiologySensitivity and SpecificityMicrobiology03 medical and health sciencesfluids and secretions0302 clinical medicineHumans030212 general & internal medicineMycological Typing TechniquesCandidaCandida glabratabiologyChromogenicCandida lusitaniaeBecton dickinsonCandidiasisGeneral Medicinebacterial infections and mycosesequipment and suppliesbiology.organism_classificationCulture MediaInfectious DiseasesCandida aurisChromogenic CompoundsCandida sppChromagar candidadescription
Abstract A shift to Candida non-albicans infections has been noted during the last years, and the emergence of multi-resistant Candida auris has complicated their management. The aim of this study was first to compare the performance of the novel chromogenic medium CHROMagar™ Candida Plus (CHROMagar, France) with CHROMagar™ Candida (Becton Dickinson, Germany) for the presumptive identification of Candida species; and then, to evaluate its utility in the detection of C. auris in surveillance samples. CHROMagar™ Candida Plus showed a good performance compared with the reference medium CHROMagar™ Candida. Sensitivity and specificity were 100% in both media for tested species at 48 h of incubation, except for Candida glabrata and Candida lusitaniae. Furthermore, the new medium allows a reliable presumptive identification of C. auris, as a new specific color for this species is assigned (light blue with a blue halo), obtaining a sensitivity and specificity of 100% at 36 h of incubation.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2020-06-29 | Diagnostic microbiology and infectious disease |