Synthesis and biological evaluation of new imidazo[2,1-b][1,3,4]thiadiazole derivatives: as anticancer and antibiofilm agents, and preclinical investigation of anti LDH-A compounds against malignant mesothelioma

6533b7dbfe1ef96bd12707c1

RESEARCH PRODUCT

Synthesis and biological evaluation of new imidazo[2,1-b][1,3,4]thiadiazole derivatives: as anticancer and antibiofilm agents, and preclinical investigation of anti LDH-A compounds against malignant mesothelioma

subject

antiproliferative activity Staphylococcal biofilm inhibitor hypoxia Anti-virulence agent pancreatic ductal adenocarcinoma chemoresistance modulation of EMT lactate dehydrogenase proton-coupled folate transporter spheroids shrinkage Settore CHIM/08 - Chimica Farmaceutica malignant pleural and peritoneal mesothelioma anti-biofilm agent imidazo[2 1-b][1 3 4]thiadiazole derivative inhibition of migration PTK2/FAK xenograft pemetrexed prognosi

year	journal	country	edition	language
2020-02-20

https://research.vumc.nl/en/publications/96463d35-c1c6-4915-abbb-f90d91393390

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