6533b7dbfe1ef96bd1270981

RESEARCH PRODUCT

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subject

0301 basic medicineBrentidaeGeneticsendocrine systemPesticide resistancebiologyBrush borderbusiness.industryWeevilfungi030106 microbiologyPest controlToxicologybiology.organism_classification03 medical and health sciencesBacillus thuringiensisBotanyPEST analysisBinding sitebusiness

description

Bacillus thuringiensis Cry3Aa and Cry3Ca proteins have been reported to be toxic against the African sweetpotato pest Cylas puncticollis. In the present work, the binding sites of these proteins in C. puncticollis brush border vesicles suggest the occurrence of different binding sites, but only one of them is shared. Our results suggest that pest resistance mediated by alteration of the shared Cry-receptor binding site might not render both Cry proteins ineffective.