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RESEARCH PRODUCT
Presence of thyroid hormones in ascidian larvae and their involvement in metamorphosis
Matteo CammarataPaolo D'agatiEleonora Patricolosubject
medicine.medical_specialtyanimal structuresmedia_common.quotation_subjectRadioimmunoassayIn vivoInternal medicinemedicineAnimalsCiona intestinalisUrochordataMetamorphosisChromatography High Pressure LiquidSwimmingmedia_commonLarvabiologyfungiMetamorphosis BiologicalRadioimmunoassayGeneral Medicinebiology.organism_classificationIn vitroThyroxineEndocrinologyLarvaThyroid hormonesAnimal Science and ZoologyHormonedescription
In this study we investigated the presence and localization of thyroxine in Ciona intestinalis larvae and its involvement in metamorphosis. To date, the mechanisms regulating the metamorphosis of ascidians remain largely unknown. In vivo treatment of swimming larvae with exogenous L-thyroxine and thiourea, and in vitro experiments utilizing high performance liquid chromatography, radioimmunoassay, and immunoperoxidase staining demonstrate the presence of thyroxine at the larval stage. This suggests that this hormone may participate in the control of metamorphosis and thus play a different role from that observed in adults.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2001-09-11 | Journal of Experimental Zoology |