6533b7dbfe1ef96bd1271334
RESEARCH PRODUCT
Der 2-(4-pyridyl)Ethoxycarbonyl-(4-Pyoc)-rest - eine hydrophile, säure- und basenstabile aminoschutzgruppe für die peptidsynthese
S. BirnbachHorst Kunzsubject
chemistry.chemical_compoundDipeptidechemistryStereochemistryMorpholineOrganic ChemistryDrug DiscoveryPeptide synthesisPyridiniumProtecting groupBiochemistryMedicinal chemistrydescription
Abstract The title amino blocking function is stable under basic and acidic conditions frequently used in the peptide synthesis. Its hydrophilicity permits an effective peptide synthesis in water. After the easy conversion to the pyridinium form the 4-Pyoc group can be removed by morpholine.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1984-01-01 | Tetrahedron Letters |