6533b7dcfe1ef96bd1272791

RESEARCH PRODUCT

Polymeric monolayers and liposomes as models for biomembranes. How to bridge the gap between polymer science and membrane biology?

Thomas FoldaRainer BüschlHelmut Ringsdorf

subject

chemistry.chemical_classificationLiposomeMembranePolymerizationchemistryVesiclePolymer chemistryMonolayerMembrane biologySurface modificationPolymer

description

This contribution deals with the stabilization of membrane model systems, especially vesicles. The desired further biological functionalization of these stabilized polymeric membranes is possible via the incorporation of proteins. Addition of natural lipids to polymerizable membranes and degradation of the unpolymerized component after polymerization allows selective opening of otherwise stable compartments. Finally, first attempts are made to combine biological properties of natural cells and the durability of polymerized membranes via fusion of synthetic vesicles with natural cells.

https://doi.org/10.1002/macp.1984.020061984119