6533b7dcfe1ef96bd12729d0
RESEARCH PRODUCT
Rational design of a fluopyram hapten and preparation of bioconjugates and antibodies for immunoanalysis
Josep V. MercaderEric Ceballos-alcantarillaConsuelo AgullóAntonio Abad-somovillaAntonio Abad-fuentessubject
InmunoanalysisbiologySDHI fungicidesGeneral Chemical EngineeringRational designTotal synthesischemical and pharmacologic phenomenaGeneral Chemistrychemistry.chemical_compoundSpecific antibodychemistryBiochemistrybiology.proteinFluopyramAntibodyHaptenHaptensdescription
A fluopyram hapten was designed in which insignificant electronic and structural modifications were foreseen and all potentially interacting chemical moieties were maintained. This hapten was prepared by total synthesis and three immunologically active bioconjugates were obtained and characterized. High-affinity and specific antibodies to fluopyram were raised.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2015-01-01 |