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RESEARCH PRODUCT

Quantitative Tissue Doppler Echocardiography: Physiological Nonuniformity of Left Ventricular Transmural Myocardial Wall-Motion Velocities and Gradients.

Michael KremerUwe NixdorffJürgen MeyerSusanne Mohr-kahalyGerd Rippin

subject

medicine.medical_specialtyReproducibilitybusiness.industryMyocardial velocityMyocardial functionTissue Doppler echocardiographyInternal medicineHealthy volunteersCardiologyMedicineRadiology Nuclear Medicine and imagingWall motionCardiology and Cardiovascular Medicinebusiness

description

Tissue Doppler echocardiography (TDE) is a new method by which transmural myocardial function can be studied noninvasively. In order to investigate physiology and reproducibility, 24 young, healthy volunteers were examined by M-mode TDE. Nonuniformity of transmural tissue layer velocities became apparent: Subendocardial and subepicardial velocities of the anteroseptal myocardial wall (AW) were 3.5 +/- 0.7 and 1.3 +/- 0.5 cm/sec (P < 0.0001, t-test), whereas in the posterolateral wall (PW) values of 3.6 +/- 0.6 and 1.2 +/- 0.4 cm/sec (P < 0.0001, t-test), respectively, were revealed. The ratios, termed "myocardial velocity gradients" as a new indicator of left ventricular performance, were 3.1 +/- 1.0 and 3.4 +/- 1.1, respectively. AW and PW did not differ (N.S.). Tolerance borders did not overlap, and intraobserver variability did not reach intersubject variability (P < 0.0001, F-ratio test). TDE provides new and more sophisticated insights into left ventricular performance. It seems to be accurate and reliable and therefore worth introducing into the clinical arena.

yearjournalcountryeditionlanguage
2001-02-15Echocardiography (Mount Kisco, N.Y.)
10.1111/j.1540-8175.1997.tb00763.xhttps://pubmed.ncbi.nlm.nih.gov/11174993