6533b7dcfe1ef96bd1272b55
RESEARCH PRODUCT
Structure determination of three polymorphs of xylazine from laboratory powder diffraction data
Anatolijs MishnevAlvis ZvirgzdinsAndris Actinssubject
Rietveld refinementHydrogen bondChemistryHydrochlorideMetals and AlloysStackingCrystal structureChlorideAtomic and Molecular Physics and OpticsElectronic Optical and Magnetic Materialschemistry.chemical_compoundCrystallographyPolymorphism (materials science)Materials ChemistrymedicinePowder diffractionmedicine.drugdescription
The crystal structures of three xylazine hydrochloride [N-(2,6-dimethylphenyl)-5,6-dihydro-4H-1,3-thiaz-2-amine hydrochloride] polymorphsA,ZandXhave been solved from powder diffraction data and refined using Rietveld refinement. Data were obtained with Cu Kα radiation. All polymorphs were found to have structures withZ′ = 1 andZ= 4. All the structures determined contained strong hydrogen bonds between the amino groups and chloride anions. The crystal structures of formsAandXfeatured π–π stacking interactions.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2014-03-28 | Acta Crystallographica Section B Structural Science, Crystal Engineering and Materials |