Tbx1 regulates Vegfr3 and is required for lymphatic vessel development

6533b7dcfe1ef96bd1272ca3

RESEARCH PRODUCT

Tbx1 regulates Vegfr3 and is required for lymphatic vessel development

Wallace L. Mckeehan Annalisa Mupo Tuong Huynh Sara Cioffi Antonio Baldini Matthew Woods Chengliu Jin Elizabeth Illingworth Elizabeth Illingworth Luann Thompson-snipes Li Chen

subject

Vascular Endothelial Growth Factor A TBX1 Cellular differentiation Biology Mice 03 medical and health sciences 0302 clinical medicine stomatognathic system Report Lymphatic vessel medicine Animals Humans Lymphangiogenesis Enhancer Cells Cultured Research Articles Lymphatic Vessels 030304 developmental biology 0303 health sciences ABNORMAL CAROTID ARTERIES; TRANSGENIC MICE; VELOCARDIOFACIAL SYNDROME; CARDIOVASCULAR DEFECTS; LYMPHANGIOGENESIS; LYMPHEDEMA; MOUSE; RECEPTOR-3; MUTATION; SYSTEM Endothelial Cells Gene Expression Regulation Developmental Cell Differentiation Cell Biology Embryo Mammalian 3. Good health Lymphangiogenesis Cell biology Vascular endothelial growth factor A Lymphatic system medicine.anatomical_structure Vascular endothelial growth factor C embryonic structures Immunology T-Box Domain Proteins 030217 neurology & neurosurgery

description

Defects in lymphangiogenesis are added to the broad clinical manifestations of DiGeorge syndrome, caused by deletion of the T box transcription factor Tbx1.

year	journal	country	edition	language
2010-05-05	Journal of Cell Biology

https://doi.org/10.1083/jcb.200912037

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