ESBL producējošu Enterobacteriaceae dzimtas baktēriju izpēte stacionētiem pacientiem

6533b7dcfe1ef96bd1272e1e

RESEARCH PRODUCT

ESBL producējošu Enterobacteriaceae dzimtas baktēriju izpēte stacionētiem pacientiem

subject

pks gēns Enterobacteriaceae ESBL nēsāšana zarnu traktā Bioloģija

description

Pēdējo gadu laikā par vienu no nopietnākajiem sabiedrības veselības apdraudējumiem visā pasaulē un arī Latvijā tiek uzskatīta antimikrobā rezistence. Arvien biežāk tiek ziņots par slimnīcas apstākļos iegūtām antibakteriālo līdzekļu rezistentu Enterobacteriaceae celmu izraisītām infekcijām. Pētījuma mērķis bija raksturot paplašināta spektra beta laktamāzes (ESBL) producējošās Enterobacteriaceae dzimtas baktērijas zarnu mikrobiotā. Apkopojot pētījuma datus, secināja, ka, izstājoties no slimnīcas, 45 (33,09%) no RAKUS 136 stacionētajiem “Biķernieki” pacientiem bija ESBL producējošo Enterobacteriaceae nēsātāji zarnu traktā. Visbiežāk sastopamais rezistences gēns (PCR metode) ESBL producējošās E. coli un K. pneumoniae, bija blaCTX-M. Papildus tika noteikts virulences gēns pks un konstatēts, ka pks sastopamība bija ļoti zema (viens no 39 DNS izolātiem). Atslēgas vārdi: Enterobacteriaceae, ESBL, pks gēns, nēsāšana zarnu traktā.

year	journal	country	edition	language
2018-01-01

https://dspace.lu.lv/dspace/handle/7/39630

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