6533b7dcfe1ef96bd1273327

RESEARCH PRODUCT

Data Sources and Models

Cristina SerraoFabio FassettiSimona E. Rombo

subject

Biological dataComputer scienceConstruct (python library)Computational biologyBiological networkNetwork modelProtein–protein interaction

description

Biological networks rely on the storage and retrieval of data associated to the physical interactions and/or functional relationships among different actors. In particular, the attention may be on the interactions among cellular components, such as proteins, genes, RNA, or for example on phenotype–genotype associations. Data from which biological networks are built are usually stored in public databases, and we provide here a brief summary of the main types of both data and associations, publicly available. Moreover, we also explain how it is possible to construct suitable network models from these associations, focusing on protein–protein interaction networks, gene–disease networks and network populations. Being the latter the model we adopted for the Part II of this book, we describe more details about it.

yearjournalcountryeditionlanguage
2017-01-01
https://doi.org/10.1007/978-3-319-63477-7_1