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RESEARCH PRODUCT
Detection Of Genomic Variants Of SARS-CoV-2 Circulating In Wastewater By High-Throughput Sequencing
ÁLvaro Chiner-omsWalter RandazzoGloria SánchezComas Espadas IMaría Alma BrachoAlba Pérez-cataluñaIrene FalcóAna AllendeGiron-guzman IEnric Cuevas-ferrandoAzahara Díaz-reolidsubject
2019-20 coronavirus outbreakCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)fungiChristian ministryBiologyVirologyDNA sequencingdescription
The use of SARS-CoV-2 metagenomics in wastewater can allow the detection of variants circulating at community level. After comparing with clinical databases, we identified three novel variants in the spike gene, and six new variants in the spike detected for the first time in Spain. We finally support the hypothesis that this approach allows the identification of unknown SARS-CoV-2 variants or detected at only low frequencies in clinical genomes.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2021-02-10 |