EFFECTS OF CELLULAR SHORT-TERM STARVATION ON CONVENTIONAL CHEMOTHERAPY RESPONSE IN HUMAN CANCER: UNDERSTANDING OF MOLECULAR MECHANISMS AND MICRORNAS INVOLVEMENT

6533b7ddfe1ef96bd127452a

RESEARCH PRODUCT

EFFECTS OF CELLULAR SHORT-TERM STARVATION ON CONVENTIONAL CHEMOTHERAPY RESPONSE IN HUMAN CANCER: UNDERSTANDING OF MOLECULAR MECHANISMS AND MICRORNAS INVOLVEMENT

subject

Settore MED/06 - Oncologia Medica Short Term Starvation Doxorubicin triple negative breast cancer microRNAs cell cultures

description

Background: Short Term Starvation (STS) is a type of dietary restriction able to reduce tumorigenesis and cancer progression but molecular bases of this effect are still unclear. Aim: In vitro analysis of STS effects in presence of chemotherapy and evaluation of microRNAs (miRNAs) involvement. Results: STS affects the expression profiles of miRNAs involved in chemotherapy response leading to cancer cells sensitization and to healthy cells protection.

year	journal	country	edition	language

http://hdl.handle.net/10447/220678

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