6533b7ddfe1ef96bd127469d

RESEARCH PRODUCT

Behavioral evaluation of aging in experimental animals

Ana Perez-villalbaIsabel Fariñas

subject

Process (engineering)Behavioral assessmentCognitionSensory systemPsychologyBody weightCognitive psychology

description

Abstract Since aging is a very a complex multisystemic process, behavioral assessment must cover a combined panoply of physical and neural functions. Behavioral measures must be objective and reproducible to be able to compare between individuals of different ages or experimental conditions. In this chapter, we discuss how aging is reflected in a very variable way in different physical, cognitive, emotional, social, motor, and sensory behaviors. We suggest specific tests to evaluate each of these functions in mice, discussing previous results obtained in different genetic strains. Finally, we identify the most distorting variables to consider, such as age range, gender, or body weight, to make a right behavioral assessment.

yearjournalcountryeditionlanguage
2021-01-01
https://doi.org/10.1016/b978-0-12-818000-6.00049-4