A simple synthesis of γ-aminoacids

6533b7ddfe1ef96bd12746ed

RESEARCH PRODUCT

A simple synthesis of γ-aminoacids

Salvador Gil Margarita Parra Pablo Rodriguez

subject

Bromoacetonitrile Chemistry Simple (abstract algebra)Organic Chemistry Drug Discovery Organic chemistry Regioselectivity Biochemistry

description

The addition of dianions of carboxylic acids to bromoacetonitrile, leads, in good yields, to the corresponding γ-cyanoacids that give γ-aminoacids on hydrogenation. This two-step methodology improves the results previously described.

year	journal	country	edition	language
2007-05-01	Tetrahedron Letters

https://doi.org/10.1016/j.tetlet.2007.03.037

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