6533b7ddfe1ef96bd1274747

RESEARCH PRODUCT

Simple models for nonlinear states of double-helix DNA

Aatto LaaksonenRaimo A. Lohikoski

subject

chemistry.chemical_compoundTheoretical physicsNucleic acid thermodynamicsNonlinear systemchemistryDenaturation (biochemistry)Statistical physicsBiologyDNA

description

Review type introduction is given to the simple modeling of DNA. Intrinsically simple modeling aims at understanding or explaining of some “core” phenomena, not giving any all-embracing model of the underlying system. As a consequence the amount of this type of models and their versions is large. Here we have restricted our contemplation to the most important lines in the path of theoretical understanding of DNA melting or denaturation which is one of the important phases occurring during DNAs replication and transcription processes. The model “line” initiated by Peyrard and Bishop shows the richness these simple models can have.

https://doi.org/10.1016/b978-044452220-7/50081-2