6533b7ddfe1ef96bd1274afa

RESEARCH PRODUCT

Determination of levamisole hydrochloride with HgI(2-)4 by a turbidimetric method and flow-injection analysis.

Campins FalcoJ. Martínez Calatayud

subject

Flow injection analysisReproducibilityChromatographyCalibration curveChemistryExtraction (chemistry)medicineTurbidimetryLevamisoleLevamisole hydrochlorideAnalytical Chemistrymedicine.drug

description

Abstract This paper is concerned with the use of ion-association compounds in the analysis of pharmaceutical samples by FIA. The usual extraction into an organic phase is avoided by using turbidimetric detection. Determination of levamisole with HgI2−4 has been developed as a practical example: the experimental variables were optimized by the modified simplex method. The calibration graph is linear over the levamisole concentration range 7–32 μ g ml . The reproducibility (rsd) and injection sample rate are 0.9% and 80/hr, respectively.

10.1016/0039-9140(86)80158-8https://pubmed.ncbi.nlm.nih.gov/18964167