6533b7ddfe1ef96bd1274b3a

RESEARCH PRODUCT

Microvascular blood flow changes of the abductor pollicis brevi muscle during sustained static exercise

Turgut DurduranTurgut DurduranUdo M. WeigelEvelina UrtaneUldis RubinsMartina GiovannellaZbignevs MarcinkevicsUmut Karadeniz

subject

medicine.medical_specialtybusiness.industryMaximum voluntary contractionVasodilationIsometric exerciseBlood flowDiffuse correlation spectroscopyThumbbody regionsmedicine.anatomical_structureInternal medicineOcclusionmedicineCardiologysense organsStatic Exercisebusiness

description

ABSTRACTA practical assessment of the health of the palm muscle, abductor pollicis brevis (APB), is important for diagnosis of different conditions. Here we have developed a protocol and a probe to utilize diffuse correlation spectroscopy (DCS) to characterize microvascular blood flow changes in the APB during and after sustained isometric exercise, during and after thumb abduction at at 55% of maximum voluntary contraction (MVC). Blood flow in the APB decreased during exercise in the subjects (n=13) with high MVC (n=7) and stayed constant in the ones with low MVC (n=6) suggesting that the mechanical occlusion due to increased intramuscular pressure exceeded the vasodilation elicited by the higher demand. Blood flow changes during exercise negatively correlated with the absolute force applied by each subject. Muscular blood flow increased after exercise compared to the values reached during exercise. In conclusion, DCS allows the study of the response of a small muscle to static exercise.

yearjournalcountryeditionlanguage
2020-06-04
10.1101/2020.06.03.20120931http://dx.doi.org/10.1101/2020.06.03.20120931