Hyaluronic acid based hydrogels for antibiotics and enzymes release: from academic research to industry

6533b7ddfe1ef96bd1274d84

RESEARCH PRODUCT

Hyaluronic acid based hydrogels for antibiotics and enzymes release: from academic research to industry

Fabio Salvatore Palumbo Giovanna Pitarresi Gaetano Giammona

subject

Hyaluronic acid drug delivery celiac disease Settore CHIM/09 - Farmaceutico Tecnologico Applicativo

description

Conclusion: HA-g-PDLLA hydrogel is suitable to coat a prosthesis remaining adherent to it and distributing itself in the bone cavity. The hydrogel has been proven effective in a rabbit model of highly contaminated implant. In vivo studies have demonstrated how the intraoperative coating of implants with DAC is safe and feasible. HA-EDA-MA hydrogel is able to protect PEP from alteration during storage and it seems a good candidate for a potential once-daily oral formulation in the treatment of celiac disease.

year	journal	country	edition	language
2016-01-01

http://hdl.handle.net/10447/207179

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