6533b7defe1ef96bd1275d3a
RESEARCH PRODUCT
Integrated optic Surface Plasmon Resonance Measurements in Glass substrates
Alessandro BusaccaLuciano CurcioS. Riva SanseverinoAlfonso Carmelo CinoE. D'asaroSaverio GuarinoAntonino ParisiFedele D'aleoG. Badalamentisubject
FabricationOpticsFiber optic sensorbusiness.industryChemistrySurface plasmonSurface plasmon resonanceThin filmbusinessBiosensorWaveguide (optics)Refractive indexdescription
The surface plasmon resonance (SPR) technique is an optical method that can be used to measure the refractive index of organic nano-layers adsorbed on a thin metal film. Although there are many techniques for measuring biomolecular interactions, SPR-based techniques play a central role in many current biosensing experiments, since they are most suited to sensitive and quantitative kinetic measurements. Here we give some results from the analysis and numerical elaboration of SPR data regarding the flow of different solutions with refractive indexes in the range of interest (1-1.4). After a brief discussion of the principles of SPR and of waveguide fabrication technique, we give a description of system setup and some results regarding the real time waveguide output intensity monitoring to measure the interaction between the gold thin film and the analyte.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2007-07-04 |