6533b7defe1ef96bd1276474

RESEARCH PRODUCT

From 160 to 20 to 1 odorant: steps in a chemo-ethological strategy to identify a mammalian pheromone

subject

description

This paper presents the strategy used to fractionate a complex odorant mixture into 20 candidate compounds, to finally single out a compound which activity explains the activity of the whole mixture. The joint chemical-behavioral approach will be outlined, and followed by a description of the experiments permitting to enter the isolated key-compound into the category of biologically-active compounds termed "pheromone".