Diels-Alder-Reaktionen von Vinylindolen mit Arin und 1,4-Benzochinonen: Neue potentielle DNA-Interkalatoren

6533b7defe1ef96bd12765d2

RESEARCH PRODUCT

Diels-Alder-Reaktionen von Vinylindolen mit Arin und 1,4-Benzochinonen: Neue potentielle DNA-Interkalatoren

Manfred Eitel Ludwig Pfeuffer M. Rogge Manfred Haber Ulf Pindur

subject

Molecular model Chemistry Intercalation (chemistry)Organic chemistry General Chemistry Aryne

description

Diels-Alder reactions of 2- and 3-vinylindoles with aryne, 1,4-benzo- and 1,4-naphtho-quinone lead to new six-ring annellated carbazoles. Molecular modeling studies predict that the compounds with coplanar framework are able to intercalate with the B-DNA.

year	journal	country	edition	language
1991-04-01	Monatshefte f�r Chemie Chemical Monthly

https://doi.org/10.1007/bf00810830

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