6533b7defe1ef96bd12766a6

RESEARCH PRODUCT

Enzyme-Mediated Controlled Release Systems by Anchoring Peptide Sequences on Mesoporous Silica Supports

Enrique Pérez-payáFélix SancenónPedro AmorósLaura MondragónRamón Martínez-máñezJuan SotoCarmen CollM. Dolores Marcos

subject

INGENIERIA DE LA CONSTRUCCIONPeptide sequencesStereochemistryPeptide hydrolaseMolecular Sequence DataAnchoringPeptideCatalysisRutheniumArticleAmino acid sequenceNanoparticleQUIMICA ORGANICACoordination ComplexesControlled release systemsSilicon dioxideControlled releaseOrganic chemistryMolecular geneticsValenciachemistry.chemical_classificationbiologyQUIMICA INORGANICAMesoporous supportSilicaGeneral ChemistryGeneral MedicineMesoporous silicaMolecular gatesbiology.organism_classificationControlled releaseMesoporous materialsChemistryKineticsEnzymeMetabolismchemistryMesoporous SilicaPeptide HydrolasesPeptideNanoparticlescontrolled releasePeptidesPorosityCoordination compoundmolecular gatesPeptide Hydrolases

description

[EN] Gated community: Peptides anchored to the surface of silica mesoporous supports by a valid procedure act as gatekeepers. In this way, "zero release" supports that selectively deliver the cargo in the presence of a suitable peptidase are obtained (see picture, red spheres: cargo, colored chains: peptides). © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

yearjournalcountryeditionlanguage
2011-02-01Angewandte Chemie
https://doi.org/10.1002/ange.201004133