6533b7defe1ef96bd12767ca

RESEARCH PRODUCT

Octaplex in routine clinical use for prophylaxis and therapy of bleeding in patients with prothrombin complex factor deficiency

M UhlJ AlbersT FrankenC NiessnerT TödterB GanseraW ReesB Sedemund-adipN Hübner

subject

medicine.medical_specialtyPediatricsbusiness.industryLiver failurePerioperativeAcute bleedingVitamin kCritical Care and Intensive Care MedicineProthrombin complex concentrateGastroenterologyCoagulationInternal medicinePoster PresentationmedicineIn patientbusinessPROTHROMBIN COMPLEXmedicine.drug

description

Octaplex is a new prothrombin complex concentrate that is indicated for treatment or perioperative prophylaxis of bleeding in patients with deficiency of the prothrombin complex coagulation factors, such as deficiency caused by treatment with vitamin K antagonists or by liver failure, when rapid correction of bleeding is required. The study was conducted to demonstrate both prevention of bleeding and achievement of haemostasis in acute bleeding and to obtain further information about the safety of administration of Octaplex.

https://doi.org/10.1186/cc5536