6533b7defe1ef96bd1276a97
RESEARCH PRODUCT
N-Heterocyclic Carbene Catalyzed Quadruple Domino Reactions through α,β-Unsaturated Acyl Azolium Intermediates : Asymmetric Synthesis of Cyclopenta[c]chromenones
Qiang LiuXiang-yu ChenRakesh PuttreddyKari RissanenDieter Enderssubject
kemiallinen synteesidomino reactionchromenoneDFT calculationorganocatalysiskumariinitN-heterocyclic carbeneorgaaniset yhdisteetdescription
An N‐heterocyclic carbene catalyzed domino sequence via α,β‐unsaturated acyl azolium intermediates has been developed. This strategy provides a convenient enantioselective route to functionalized tricyclic coumarin derivatives and cyclopentanes. DFT studies and control experiments were performed to gain better insight into the reaction mechanism. peerReviewed
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2018-01-01 |