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RESEARCH PRODUCT

Techniques To Control Polymersome Size

Regina BleulMichael MaskosMichael MaskosRaphael Thiermann

subject

Inorganic ChemistryPreparation methodPolymers and PlasticsComputer scienceOrganic ChemistryPolymersomeDrug deliveryMaterials ChemistryNanomedicineContext (language use)Nanotechnology

description

Polymersomes as synthetic analogues of liposomes appear frequently in relevant literature as promising candidates for a wide range of different applications including drug delivery, theranostic multitools, and nanoreactors. In particular, as nanotransporters for nanomedical applications in vivo, requirements concerning the reproducible manufacturing and reliable size control are extremely high. This Perspective highlights the importance of size control especially in the context of nanomedicine and gives an overview of the theoretical background of amphiphilic self-assembly leading to different preparation methods, where their feasibility of controlling polymersomes’ size is discussed.

yearjournalcountryeditionlanguage
2015-10-12Macromolecules
https://doi.org/10.1021/acs.macromol.5b01500