6533b81ffe1ef96bd12770d5
RESEARCH PRODUCT
Point Mutation Rate of Bacteriophage ΦX174
Siobain DuffyJosé M. CuevasRafael Sanjuánsubject
GeneticsbiologyPoint mutationGenome Viralbiology.organism_classificationmedicine.disease_causeMolecular biologyGenomePhenotypeBacteriophagechemistry.chemical_compoundchemistryNotesDNA ViralEscherichia coliGeneticsmedicinePoint MutationDna viralEscherichia coliBacteriophage phi X 174DNAdescription
Abstract The point mutation rate of phage ΦX174 was determined using the fluctuation test. After identifying the genetic changes associated with the selected phenotype, we obtained an estimate of 1.0 × 10−6 substitutions per base per round of copying, which is consistent with Drake's rule (0.003 mutations per genome per round of copying in DNA-based microorganisms).
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2009-10-01 | Genetics |