6533b81ffe1ef96bd127711a

RESEARCH PRODUCT

Synthesis of 7-Pentafluorophenyl-1H-indole: An Anion Receptor for Anion–π Interactions

Markus AlbrechtKari RissanenMichael GieseFangfang PanFangfang PanZhanhu Sun

subject

Indole testMolecular recognitionChemistryStereochemistryOrganic ChemistryChemieHalideBartoli indole synthesisAnion bindingCombinatorial chemistryAnion receptorCoupling reactionIon

description

7-Pentafluorophenyl-1H-indole has the potential to be a key compound for the investigation of anion–π interactions in solution. Unfortunately, it was not possible to obtain it by aryl–aryl coupling reaction. Finally, it has been prepared by Bartoli indole synthesis. The key compound as well as analogues were submitted to preliminary studies of anion binding. Single crystals of two key receptors were obtained.

yearjournalcountryeditionlanguage
2014-07-16Synlett
https://doi.org/10.1055/s-0034-1378449