Structure of mammalian plasma fetuin-B and its mechanism of selective metallopeptidase inhibition

6533b81ffe1ef96bd12771bd

RESEARCH PRODUCT

Structure of mammalian plasma fetuin-B and its mechanism of selective metallopeptidase inhibition

Anna Cuppari Hagen Körschgen Daniele De Sanctis Theodoros Goulas Ralf Weiskirchen Willi Jahnen-dechent Julia Floehr Walter Stoecker Luca Jovine F. Xavier Gomis-rüth Dirk Fahrenkamp Carlo Schmitz Tibisay Guevara Konstantin Karmilin Michael Kuske Mario Olf Eileen Dietzel Irene Yiallouros

subject

Crystallography mammalian fertilization metallopeptidase Research Papers structure determination 570 Life sciences enzyme mechanisms protein inhibitor QD901-999 multi-protein complexes sperm–egg fusion polyspermy protein structure X-ray crystallography 570 Biowissenschaften

description

The co-crystal structure of the metallopeptidase astacin with its specific protein inhibitor fetuin-B reveals a novel mechanism of inhibition.

year	journal	country	edition	language
2018-11-13

https://dx.doi.org/10.25358/openscience-768

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