Collaborative roles of Temporoparietal Junction and Dorsolateral Prefrontal Cortex in Different Types of Behavioural Flexibility

6533b81ffe1ef96bd127739d

RESEARCH PRODUCT

Collaborative roles of Temporoparietal Junction and Dorsolateral Prefrontal Cortex in Different Types of Behavioural Flexibility

Kathryn F. Jankowski Nobuhito Abe Junya Fujino Junya Fujino Genichi Sugihara Ryosaku Kawada Jun Miyata Toshiya Murai Jukka-pekka Kauppi Jukka-pekka Kauppi Hidehiko Takahashi Shisei Tei Shisei Tei Shisei Tei Wouter Van Den Bos

subject

Male NEURAL BASIS Brain activity and meditation Decision temporoparietal junction BRAIN ACTIVITY Neuropsychological Tests 3124 Neurology and psychiatry 0302 clinical medicine Parietal Lobe Attention media_common prefrontal cortex Multidisciplinary Shifting attention 05 social sciences Q Cognitive flexibility R Flexibility (personality)Magnetic Resonance Imaging Temporal Lobe medicine.anatomical_structure Social behaviour ECONOMIC DECISION-MAKING Medicine Female Psychology ULTIMATUM GAME Cognitive psychology 515 Psychology media_common.quotation_subject Science Temporoparietal junction SPATIAL ATTENTION Prefrontal Cortex Morals 050105 experimental psychology Article 03 medical and health sciences Young Adult Perception medicine Humans 0501 psychology and cognitive sciences Social Behavior PARIETAL JUNCTION Mechanism (biology)collaborative roles STIMULUS-DRIVEN ATTENTION Dorsolateral prefrontal cortex MORAL JUDGMENT TASK COGNITIVE FLEXIBILITY 030217 neurology & neurosurgery

description

AbstractBehavioural flexibility is essential for everyday life. This involves shifting attention between different perspectives. Previous studies suggest that flexibility is mainly subserved by the dorsolateral prefrontal cortex (DLPFC). However, although rarely emphasized, the temporoparietal junction (TPJ) is frequently recruited during flexible behaviour. A crucial question is whether TPJ plays a role in different types of flexibility, compared to its limited role in perceptual flexibility. We hypothesized that TPJ activity during diverse flexibility tasks plays a common role in stimulus-driven attention-shifting, thereby contributing to different types of flexibility, and thus the collaboration between DLPFC and TPJ might serve as a more appropriate mechanism than DLPFC alone. We used fMRI to measure DLPFC/TPJ activity recruited during moral flexibility, and examined its effect on other domains of flexibility (economic/perceptual). Here, we show the additional, yet crucial role of TPJ: a combined DLPFC/TPJ activity predicted flexibility, regardless of domain. Different types of flexibility might rely on more basic attention-shifting, which highlights the behavioural significance of alternatives.

year	journal	country	edition	language
2017-07-25	Scientific Reports

http://hdl.handle.net/2433/228154