6533b81ffe1ef96bd12779f2

RESEARCH PRODUCT

ChemInform Abstract: Total Synthesis of (+)-Greek Tobacco Lactone.

Juha H. SiitonenPetri M. Pihko

subject

chemistry.chemical_classificationStereospecificityChemistryStereochemistryEnantioselective synthesisOrganic chemistryTotal synthesisGeneral MedicineLactone

description

An enantioselective, protecting-group-free, total synthesis of (+)-Greek tobacco lactone has been achieved by using an organocatalytic Mukaiyama–Michael reaction and a stereospecific oxa-Michael reaction as key steps.

https://doi.org/10.1002/chin.201507269