6533b81ffe1ef96bd127828b

RESEARCH PRODUCT

2018 Consensus of the French Society of Endocrinology: endocrine toxicities of cancer immunotherapies

Frederic CastinettiFrancoise Borson-chazotFrederique AibarelFrancoise ArchambeaudJerome BertheratBenjamin BouilletPerrine BuffierClaire BrietBertrand CariouPhilippe CaronOlivier ChabrePhilippe ChansonChristine CortetChristine Do CaoDelphine DruiMagali HaissaguerreSegolene HescotFrederic IllouzEmmanuelle KuhnNajiba LahlouEmilie MerlenVeronique RaverotSarra SmatiBruno VergesConsensus Sfe 2018

subject

Thyroiditis[SDV.GEN]Life Sciences [q-bio]/GeneticsDiabetes[SDV.GEN] Life Sciences [q-bio]/GeneticsImmunotherapyHypophysitisAdrenal insufficiency

description

Immunotherapy induced side effects: Are frequent, usually well-tolerated, and can lead to thyroid, pituitary, and less frequently adrenals and pancreas (fulminant diabetes) disease,. Do not contra-indicate immunotherapy, and rarely require high dose glucocorticoids; Need to be screened for, as there are acute manifestations, and replacement treatments can be given lifelong; Require a pre-immunotherapy evaluation; Require a careful follow-up at least during the first 6 months of immunotherapy.

yearjournalcountryeditionlanguage
2019-01-01
https://hal.archives-ouvertes.fr/hal-02478900