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RESEARCH PRODUCT
Updated overview on interplay between physical exercise, neurotrophins, and cognitive function in humans
Camilla MattiuzziGiuseppe LippiFabian Sanchis-gomarsubject
Nerve Tissue ProteinsPhysical Therapy Sports Therapy and RehabilitationPhysical exerciseReceptors Nerve Growth Factorneurotrophins03 medical and health sciencesCognition0302 clinical medicineNeurotrophin 3Neurotrophic factorsphysical exerciseRegular PaperHumansMedicineAerobic exerciseOrthopedics and Sports MedicineNerve Growth Factors030212 general & internal medicineExercisephysical exercise neurotrophins cognitive functioncognitive functionSportbiologybusiness.industryBrain-Derived Neurotrophic FactorCognition030229 sport sciencesNerve growth factorSynaptic plasticitybiology.proteinbusinessNeuroscienceNeurocognitiveNeurotrophindescription
Highlights • Physical exercise maintains or improves cognitive functions, and neurotrophin receptor signaling may play an important role. • A positive relationship exists between physical exercise and circulating brain-derived neurotrophic factor levels. • Less clear evidence has been found for a relationship between physical exercise and other neurotrophin levels, such as nerve growth factor, neurotrophin-3, and neurotrophin-4. • The postexercise variation of brain-derived neurotrophic factor might be associated with improvement of neurocognitive functioning. • Physical exercise may be an inexpensive and safe strategy for boosting brain-derived neurotrophic factor release, thus preserving or restoring cognitive function.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2019-09-01 |