Spectrophotometric estimation of bicalutamide in tablets

6533b81ffe1ef96bd1278716

RESEARCH PRODUCT

Spectrophotometric estimation of bicalutamide in tablets

Yogesh Pore Sancheti Pp Manali Shah Poonam Karekar Vyas Vm

subject

Detection limit Chromatography Bicalutamide Chemistry Short Communication tablet dosage forms Analytical chemistry Pharmaceutical Science Molar absorptivity Dosage form Absorbance Ultraviolet visible spectroscopy Bicalutamide medicine UV spectroscopy medicine.drug

description

A simple, sensitive, rapid, accurate and precise spectrophotometric method has been developed for the estimation of bicalutamide in bulk and pharmaceutical dosage forms. Bicalutamide shows maximum absorbance at 272 nm with molar absorptivity of 2.3399×10(4) l/mol/cm. Beer's law was obeyed in the concentration range of 1.5-18 μg/ml. The limit of detection and limit of quantification were found to be 0.1 and 0.4 μg/ml, respectively. Results of analysis were validated statistically and by recovery studies.

year	journal	country	edition	language
2007-09-26	Indian Journal of Pharmaceutical Sciences

https://doi.org/10.4103/0250-474x.49131

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