6533b81ffe1ef96bd1278e8f

RESEARCH PRODUCT

BOGENVI: A Biomedical Ontology for Modelling Gene*Environment Interactions on Intermediate Phenotypes in Nutrigenomics Research

Olga PortolésA. FabregatDolores CorellaE. BarreraM. ArreguiOscar Coltell

subject

Nutritional genomicsbusiness.industryComputer scienceGenomicsWeb engineeringOntology (information science)computer.software_genreData scienceHealth informaticsComputingMethodologies_PATTERNRECOGNITIONNutrigenomicsInformation systemWeb servicebusinesscomputer

description

Nutritional Genomics is demanding computing models and technological platforms in order to support acquisition, storage, management and presentation of all the information generated coming from heterogeneous sources: genotypes, environmental factors (diet and other life-style factors) and phenotypes (intermediate and final phenotypes). Our aim is to build a biomedical ontology in order to modelling gene*environment interactions on intermediate phenotypes by means of formalising and integrating genomic, environmental and phenotypic data, in the field of research on Nutritional Genomics applied to cardiovascular diseases and associated phenotypes. This ontology is part of a Health Information System based on Web engineering technologies, architectures and services, and integrating several data types to support Nutritional Genomics research in cardiovascular diseases.

https://doi.org/10.1109/cbms.2008.83